腹膜透析与血液透析对肾性贫血的疗效观察

摘要

Objective To compare the effect of peritoneal dialysis( PD ) and hemodialysis ( HD ) on improving the renal anemia. Methods 31 cases of uremic patients were divided into two groups randomly, 13 cases of peritoneal dialysis( PD group ), 18 cases of hemodialysis( HD group ). The erythropoietin was not used at the beginning of the therapy, but added after 1 month of therapy, and the levocarnitine was combined with erythropoietin after 2 months of therapy. The hemoglobin( Hb ) levels of pre-dialysis and 1,2 and 3months post-dialysis of two groups were compared. Results Hb values of the two groups before dialysis was not significantly different (P >0.05 ). Hb value after 1 month,2 month,3 months of treatment were significantly increased from the pre-dialysis( P <0.01 ). Conclusion PD and HD can improve the state of anemia in uremia,and the effect of PD is superior to HD. Erythropoietin has a good regulating effect on the state of anemia induced by uremia,and the curative effect was more apparent when combined with levocarnitine.%目的 比较腹膜透析(PD)与血液透析(HD)改善肾性贫血的疗效.方法 将31例尿毒症患者随机分为PD组(13例)和HD组(18例).两组开始治疗时均未使用促红细胞生成素,治疗1个月后均加用促红细胞生成素,治疗2个月时均增加左卡尼汀联合促红细胞生成素进行治疗.比较分析两组患者透析前及透析后1、2、3个月的血红蛋白(Hb)变化.结果 PD组和HD组的Hb值在透析治疗前未见显著差异(P＞0.05);两组Hb值在治疗1、2、3个月后与透析前比较显著升高P＜0.01).结论 PD和HD均能改善尿毒症贫血状态,而PD效果优于HD,促红细胞生成素对尿毒症导致肾性贫血状态有较好调节作用,联合左卡尼汀治疗效果更加明显.