良性前列腺增生患者经尿道前列腺电切术后并发尿路感染的相关因素分析

摘要

Objective To analyze the related factors for urinary tract infections in patients with benign prostatic hyperplasia after transurethral resection of the prostate to cause clinical attention. Methods 570 cases of clinical information of BPH were collected in department of urinary surgery of our hospital from De-cember 2009 to January 2013. The relevant factors of urinary tract infection After TURP were analyzed. Re-sults 86 cases of urinary tract infection in 570 patients with BPH after TURP,urinary tract infection rate was 15. 1%. These factors of Age> 65 years,low seniority surgery,preoperative urinary retention and the line catheterization,BPH combined diabetes,preoperative prophylactic antibiotics,surgical time > 1 h and postoperative indwelling catheter for too long were leading to postoperative urinary tract infection statistically significant single factor. BPH patients with diabetes mellitus (OR 2. 71,95% CI 1. 26~3. 58),urinary reten-tion preoperatively line catheterization (OR 3. 30,95% CI 2. 92~11. 54),indwelling catheter time >6 d (OR 2. 96,95% CI 1. 38~10. 52) is a urinary tract infection occurs after TURP risk factors. The preopera-tive prophylactic antibiotics (OR 1. 82,95% CI 1. 05~19. 78) was a protective factor. Conclusion Preop-erative diabetes,urinary retention,prolonged indwelling catheter after TURP are causing urinary tract infec-tion risk factors,should be reasonable control of blood glucose,prophylactic antibiotics,shortening catheter time,removal of the catheter as soon as possible in order to reduce the incidence of urinary tract infection af-ter TURP.%目的：分析良性前列腺增生( BPH)患者经尿道前列腺电切( TURP)术后并发尿路感染的相关因素,以引起临床重视。方法收集芜湖市第一人民医院泌尿外科2009年12月至2013年1月收治的接受TURP的BPH患者570例,对影响TURP术后尿路感染的相关因素进行分析。结果570例BPH患者TURP术后发生尿路感染者86例,尿路感染发生率为15.1%。年龄>65岁、术者年资较低、术前有尿潴留而行导尿术,BPH合并糖尿病、术前未预防性使用抗生素、手术时间>1 h及术后留置导管时间>6 d是导致术后尿路感染的具有统计学意义的单因素；BPH患者合并糖尿病( OR 2.71,95%CI 1.26~3.58)、术前因尿潴留行导尿术(OR 3.30,95%CI 2.92~11.54)、留置导管时间>6 d (OR 2.96,95%CI 1.38~10.52)是TURP术后发生尿路感染的危险因素；而术前预防性使用抗生素(OR 1.82,95%CI 1.05~19.78)是保护因素。结论术前合并糖尿病、尿潴留、留置导管时间>6 d是导致TURP术后尿路感染的危险因素,应合理控制患者血糖,预防性应用抗生素,缩短导管留置时间,尽早拔除导尿管以降低TURP术后尿路感染的发生。