树突状细胞在慢性阻塞性肺疾病中的研究进展

摘要

树突状细胞（ DCs）作为免疫应答的启动者，是构成免疫系统的核心成分，在一些自身免疫性疾病的发病中有重要的作用。慢性阻塞性肺疾病（ COPD）是一种常见的肺部炎症性疾病，而且可能是一种自身免疫性疾病。越来越多的研究提示DCs参与了COPD的发病过程，但相关研究并不深入。临床医师和学者们应进一步研究DCs与 COPD 的关系，为 COPD 的诊治提供新的思路，从而降低COPD的患病率和病死率，提高人们的生活质量。%Dendritic cells (DCs) as the promoter of immune responses,are the key components of the immune system,and it has been confirmed that DCs have an important role in the pathogenesis of some auto-immune diseases.Chronic obstructive pulmonary disease ( COPD ) is a common pulmonary inflammatory disease,and it may also be an autoimmune disease.An increasing number of studies suggest that DCs are involved in the pathogenesis of COPD,but the related studies are not deep enough.Clinicians and scholars should further study the relationship between COPD and DCs , and provide new ideas for the diagnosis and treatment of COPD,so as to reduce the morbidity and mortality of COPD,and improve people′s quality of life.