神经调节干预技术在强迫症中的应用进展

摘要

强迫症是一种较为难治的精神疾病,有相当一部分患者经充分的药物治疗和心理治疗,症状仍不能完全缓解.神经调节干预技术是一种新兴的治疗手段,具有较高的治疗潜力,近年来在强迫症中的应用取得了初步进展.神经调节干预技术包括电休克、重复经颅磁刺激以及深部脑刺激,电休克技术可选择性应用于共病其他精神障碍的患者;重复经颅磁刺激是一种非侵入性技术,可作为强迫症患者一种新的增效途径;而深部脑刺激作为一种侵入性技术,疗效确切,易被患者和医师所接受.%Obsessive-compulsive disorder(OCD) is an intractable mental disorder .A considerable number of patients are still unable to achieve full remission after adequate medication and psychotherapy .Neuromodulation intervention is a new treatment with high potential ,and preliminary progress has been made in the application for OCD in recent years .Neuromod-ulation interventions include electroconvulsive therapy ,repetitive transcranial magnetic stimulation and deep brain stimula-tion.Electroconvulsive therapy can be applied to OCD comorbid other mental disorders ; repetitive transcranial magnetic stimulation is a noninvasive technique that can be used as a new augmentation strategy for patients with OCD ;deep brain stimulation,as an invasive technique ,because of its exact efficacy ,is easy to be accepted by the patients and doctors .