子宫锭治疗宫颈锥切术后持续高危型HPV感染的临床疗效观察

摘要

Objective To observe the clinical efficacy of uterine ingot therapy for persistent high-risk human papillo-mavirus(HPV) infection after cervical conization .Methods From Jan.2015 to Dec.2016,70 patients with high-risk HPV infection after cervical conization treated at the gynecology clinic of the Chinese Medicine Hospital Affiliated to Xin -jiang Medical University were randomly divided into an observation group and a control group ,35 cases in each group .The observation group was given 1 tablet of uterine ingot once every 5 days on the cervix and 4 times as one course of treatment;the control group was given Baofukang suppository 2 capsules on the cervix for 7 days as a course of treatment .The above two groups were treated continuously for 3 courses.Results The two groups were mainly infected by HPV16 and HPV18. The rate of negative conversion of high-risk HPV in the uterine ingot group was higher than that of Baofukang suppository group[77.14%(27/35) vs 54.29%(19/35),P<0.05].There was no significant difference in clinical efficacy of tradi-tional Chinese medicine(P>0.05).Conclusion Uterine ingot can effectively reduce the high-risk HPV infection load, which can effectively improve the clinical symptoms ,especially in patients with cervical erosion and contact bleeding .%目的 观察子宫锭治疗宫颈锥切术后持续高危型人乳头瘤病毒(HPV)感染的临床疗效.方法 选择2015年1月至2016年12月就诊于新疆医科大学附属中医医院妇科门诊的宫颈锥切术后伴随有高危型HPV感染的患者70例,按随机数字法分为观察组和对照组,各35例.观察组子宫锭1片每5天宫颈上药1次,4次为1个疗程;对照组保妇康栓2粒宫颈上药7 d为1个疗程,以上两组均连续治疗3个疗程.结果 两组均以HPV16、HPV18感染为主.子宫锭组对于高危型HPV的痊愈率高于保妇康栓组[77.14%(27/35)比54.29%(19/35),P<0.05].中医临床疗效比较,差异无统计学意义(P>0.05).结论 子宫锭能有效降低宫颈高危型HPV感染,可以有效改善患者的临床症状,尤其对宫颈糜烂及接触性出血的患者疗效更佳.