目的：探讨咽拭子肺炎支原体（MP）培养法结合血清MP-IgM抗体检测在小儿MP肺炎诊断过程中的临床意义，为临床早期快速、准确诊断MP肺炎提供临床依据。方法：同时采用两种MP检测法对350例临床确诊为肺炎的患儿的咽拭子和血清标本进行检测，每个患儿取咽拭子做快速培养和血清做MP-IgM抗体检测，对两种方法的检测结果进行统计并与临床诊断治疗病例进行回顾性分析。结果：咽拭培养法检出阳性41例，阳性率为11.7%；血清MP-IgM抗体测出阳性81例，阳性率23.1%；41例MP咽拭培养阳性患者中，血清MP-IgM抗体测出阳性17例，阳性率41.5%；以上两种检测结果任意一项阳性病例合计为105例，阳性率为30%，明显高于单一使用血清MP-IgM抗体和咽拭培养的阳性率。结论：二种检测方法的同时使用可明显提高早期小儿肺炎支原体肺炎诊断率，临床医生应根据患儿病程，加以使用。%Objective:To investigate the clinical significance of pharyngeal swab culture of mycoplasma combined with MP-Ig M levels in children with mycoplasma pneumonia (MP) in the diagnosis process , so as to provide clinical evidence for rapid, accurate diagnosis of MP early.Methods:The simultaneous detection of 350 cases of pneumonia in children pharyngeal swabs and serum samples, each child from pharyngeal swab do fast culture and detect serum MP-IgM levels. Statistical results of detection of two kinds of methods and the clinical diagnosis and treatment of cases were retrospectively analyzed.Results:Pharyngeal swab culture was positive in 41 cases, the positive rate was 11.7%. Serum MP-IgM levels test positive in 81 cases, the positive rate was 23.1%.In 41 cases of mycoplasma culture in pharyngeal swab positive patients, serum MP-IgM levels test positive in 17 cases, the positive rate was 41.5%. The total number of the above two kinds of detection results of an arbitrary positive cases is 105 cases, the positive rate was 30%. It is significantly higher than that of the positive rate of serum MP-IgM levels or pharyngeal swab culture.Conclusions:The two detection methods used combine at the same time can significantly improve the rate of early diagnosis of children with mycoplasma pneumonia, clinicians should be used according to children with disease.
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