冠心病合并2型糖尿病患者的临床表现及冠脉造影特点

摘要

目的:探讨冠心病合并2型糖尿病患者的临床表现及冠脉病变的特点.方法:选择148例经冠脉造影确诊为冠心病的患者,其中合并2型糖尿病的患者共70例作为观察组,未合并2型糖尿病的患者共78例作为对照组,分析比较两组的临床资料及冠脉病变特点.结果:观察组与对照组的年龄、性别、高血压、高血脂病史和吸烟史之间差异无显著性(P＞0.05),现察组低密度脂蛋白(LDL-L)、甘油三酯(TG)水平显著高于对照组,而高密度脂蛋白(HDL-L)水平显著低于对照组(P＜0.05),观察组冠脉病变以多支病变和弥漫性病变为主,狭窄程度严重(P＜0.05).结论:冠心痛件2型糖尿病患者血脂紊乱曼显著,常累及多支冠状动脉,病变呈弥漫性.%Objective To study the clinical manifestations and coronary artery disease features in coronary heart disease(CHD) patients with type 2 diabetes mellitus(DM). Methods 148 patients with coronary heart disease diagnosed by coronary angiography were involved in the present study, in which 70 patients with DM as the observation group and 78 patients without DM as the control group. The clinical characters and coronary angiographic features were analyzed.Results Age, sex, hypertension, hyperlipidemia and smoking history had no significant difference between two groups (P＞0.05 ). The TG, LDL-L levels in the observation group were significantly higher than the control group, and the HDL-L level is significantly lower( P＜0.05 ), the coronary artery lesions of observation group is dominated by multi-vessel disease and diffuse lesions, the stenosis is severe(P＜0. 05). Conclusion Dyslipidemia is more pronounced in patients with coronary heart disease and type 2 diabetes mellitus, the characteristics of coronary artery lesions is multi-vessel,widespread and diffused.