血清TBA CHE及PA联合检测在不同类型肝病诊断中的应用

摘要

目的 探讨血清总胆汁酸(TBA)、胆碱酯酶(CHE)及前白蛋白(PA)在不同类型肝病诊断中的应用.方法 检测32例健康对照者和175例不同类型肝病患者的血清TBA、CHE及PAB等指标,并对结果进行分析.结果 与对照组相比,除慢性肝炎轻度组外,其它各组血清TBA水平均显著高于正常对照(P＜0.01),且以急性肝炎最高；与对照组相比,急性肝炎组、慢性肝炎轻度组和肝癌组的血清CHE水平无统计学意义(P＞0.05)；慢性肝炎中、重度组以及肝硬化组,其血清CHE水平明显降低(P＜0.01)；与对照组比较,除急性肝炎和慢性肝炎轻度组外,其它各组血清PA水平差异均有统计学意义(P＜0.01).结论 TBA、CHE和PA在不同类型肝病诊断中具有一定的实用价值.%Objective To investigate the application of serum total bile acid (TBA), cholinesterase (CHE) and prealbumin (PA) on diagnosing different types of liver disease. Methods The serum TBA, CHE, and PAB of 32 health-y controls and 175 patients with different types of liver disease were detected, and the results were analyzed. Results Compared with the control group, the level of TBA in other patients was significantly higher than normal controls (P< 0. 01) , except mild chronic hepatitis group, and the highest in acute hepatitis; Compared with the control group, the level of CHE in acute hepatitis group, chronic hepatitis group and liver cancer group was no significant difference (P> 0. 05) ; The level of CHE in chronic hepatitis moderate group,severe group, and cirrhosis group decreased significantly (P<0. 01) ; Compared with the control group, the level of PA in other groups had a significant differences(P<0. 01) ; except mild acute hepatitis and chronic hepatitis group. Conclusion The diagnosis of TBA, CHE, and PA on different types of liver disease has some practical value,