Application value of Serum Hs-CRP, IL-6 and plasma FIB joint detection in COPD

摘要

Objective:To discuss the application value of High sensitivity C-reactive protein (Hs-CRP), interleukin-6 (IL-6) and fibrinogen (FIB) joint detection in chronic obstructive pulmonary disease (COPD).Methods:A total of 181 COPD cases were divided to be COPD stable phase group (65 cases) and COPD acute exacerbation phase group (116 cases) per the course of disease. COPD acute exacerbation phase group was classified into grade I (39 cases), grade II (43 cases) and grade III (34 cases) based on pulmonary function. Then survival group (87 cases) and death group (29 cases) were divided based on illness transition. Meanwhile, 80 cases of healthy people at the same phase were set to be healthy group. Differences in levels of Serum hs-CRP, IL-6 and FIB in these groups were analyzed, and according to these indexes, prognostic potency of COPD acute exacerbation phase could be evaluated.Results:Difference in serum hs-CRP, IL-6 and FIB levels in COPD stable phase group, COPD acute exacerbation phase group and healthy group were statistical significant (P<0.05). both for healthy group