药源性过敏性休克的文献分析

摘要

目的：分析药源性过敏性休克的基本情况及发生原因。方法：检索中文医药卫生期刊2000年-2013年报道的药源性过敏性休克个案进行分析。结果：一百多种药物可引起过敏性休克,发生率最高的为抗生素,90%发生在用药后30分钟以内。文中还对药源性过敏性休克的原因进行了分析。结论：用药前询问过敏史,严格用药指征,观察用药后反应,方能确保用药安全。%Objective:To analyses the aspects of drug-induced allergic shock and its causes. Methods:The case reports of drug-induced allergic shock, published on Chinese medical periodicals during the period of 2000 to 2013, were collected and ana-lyzed. Results:The drug-induced allergic shock was caused by over one hundred drugs, occurring within 30 minutes after drug admin-istration in 90% of the patients, mostly by antibiotics. The reasons for the drug-induced allergic shock were also analyzed in this pa-per. Conclusions:Allergic history should be taken in detail before the use, the indications of drug use are strictly controlled and the drug adverse reaction are observed so as to ensure the safe use of the drugs.