Objective: To investigate current situation of Aspirin use in prevention of cardio-cerebrovascular diseases in Shanghai pension institutions. Methods:The related baseline data were collected from the hospitalized elderly in Shanghai social wel-fare institutions, including demographics, laboratory tests, the use of antiplatelet drugs, cardio-cerebrovascular events and so on. Based on "Chinese guidelines for prevention of cardiovascular diseases" and "Chinese guidelines for primary prevention of stroke, 2010", the actual usage rate of Aspirin for the primary prevention of cardiovascular diseases in the overall population was calculated. According to "Chinese guidelines for prevention of cardiovascular diseases" and"Chinese guidelines for secondary prevention of ische-mic stroke and transient ischemic attack, 2010 ", the actual usage rate of Aspirin was calculated. As for hypertension and diabetes subgroups, on the basis of "Chinese guidelines for prevention and treatment of hypertension, 2010" and "Chinese guidelines for pre-vention and treatment of type 2 diabetes (2013), the actual usage rate of Aspirin was acquired. Results:396 cases from 563 valid questionnaires were diagnosed with cardio-cerebrovascular diseases. Among them, 18 cases were suitable for the primary prevention, 4 cases had taken Aspirin, and the actual usage rate was 22. 22%. 396 cases were suitable for the secondary prevention, 140 cases had taken the drug, and the usage rate was 35. 35%. 11 cases of hypertensive subgroups were appropriate for the primary prevention, 2 ca-ses had taken the drug, and the actual usage rate was 18. 18%. 334 cases were fitted for the secondary prevention, 125 cases had taken the drug, and the usage rate of 37. 43%. Six cases in diabetic subgroups were suitable for the primary prevention, actually one case had taken the drug with the use rate of 16. 67%. 112 patients were suitable for the secondary prevention, 46 cases were treated with the drug, accounting for 41. 07%. Among 149 cases unsuitable for the primary prevention of cardiovascular diseases, Aspirin was administrated to 14 people with the actual usage rate of 9. 40%. Among those suitable for the primary prevention of cardiovascular dis-eases, 6 cases had taken Aspirin, while 2 cases of them stopped taking the drug with the discontinuation rate of 33. 33%. Among 178 cases of the secondary prevention, 38 cases stop taking aspirin with the discontinuation rate of 21. 35%. For all of the population tak-ing Aspirin, 96. 20% were treated once per day, 3. 80% were once every other day, all with a regular use;and the dose of 98. 10%people followed the national guidelines. Conclusions:For the population in Shanghai pension institutions of the primary and secondary prevention of cardiovascular and cerebrovascular diseases, the Aspirin usage rate is lower, but the situations of irrational use and stop taking Aspirin exist.%目的：：了解阿司匹林在上海市属养老机构心脑血管疾病患者预防中的应用现状。方法：收集上海市属社会福利院的住院老年人相关基线资料：包括人口学、实验室检查、抗血小板药物使用、心脑血管事件发生情况等。总体人群心脑血管一级预防依据中国心血管病预防指南及中国卒中一级预防指南2010的推荐,计算阿司匹林实际使用率；二级预防按照中国心血管病预防指南,中国缺血性脑卒中和短暂性脑缺血发作二级预防指南2010相关推荐,计算阿司匹林实际使用率。高血压和糖尿病亚组则分别依据中国高血压防治指南2010和中国2型糖尿病防治指南(2013)的相关推荐计算阿司匹林实际使用率。结果：563份有效调查表中396例患者有明确的心脑血管疾病。符合一级预防人群18例,实际服用4例,使用率为22.22%,符合二级预防人群396例,实际服用140例,使用率为35.35%；高血压亚组患者符合一级预防人群11例,实际服用2例,使用率为18.18%,符合二级预防人群334例,实际服用125例,使用率为37.43%。糖尿病亚组患者符合一级预防人群6例,实际服用1例,使用率为16.67%,符合二级预防人群112例,实际服用46例,使用率为41.07%。不符合指南推荐的心脑血管疾病一级预防人群149例,实际服用阿司匹林14例,不合理使用率9.40%。心脑血管疾病一级预防人群中曾服用阿司匹林者6例,停止服用2例,停用率33.33%,二级预防人群178例,停止服用38例,停用率21.35%。所有服用阿司匹林的人群中,96.20%为每日1次,3.80%为隔日1次,无不规律服用,98.10%人群服用剂量符合国内个指南的推荐剂量。结论：上海市属养老机构心脑血管疾病一级预防和二级预防人群阿司匹林使用率偏低,同时还存在不合理使用及停服阿司匹林的情况。
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