超声引导下甲氨蝶呤局部注射在异位妊娠治疗中的效果观察

摘要

目的：研究超声引导下甲氨蝶呤局部注射在异位妊娠治疗中的效果。方法：将46例患者按随机对照法分为试验组（n=23）和对照组（n=23），对照组采用甲氨蝶呤静脉滴注，试验组采用超声引导甲氨蝶呤局部注射，且两组患者同时口服米非司酮，比较两组患者治疗后的临床效果、血β-hCG下降率及不良反应发生情况。结果：试验组有效率优于对照组，包块缩小>30%例数多于对照组，平均住院时间及不良反应发生率均少于对照组，两组上述指标比较差异具有统计学意义（P<0.05）；两组治疗后血β-hCG较治疗前均下降，试验组下降较为明显（P<0.05）。结论：超声引导下甲氨蝶呤局部注射治疗异位妊娠取得较好效果，有效减少不良反应，利于患者早日康复。%Objective:To study the effect for ultrasound guided methotrexate local injection in the treatment of ectopic pregnancy. Method:46 patients were randomly divided into two groups,namely the experimental group(n=23)and the control group(n=23)according to the randomized controlled method,the control group was taken with methotrexate infusion,and the experimental group was taken with ultrasound guided methotrexate local injection,and the two groups all took oral mifepristone at the same time. The clinical effects between the two groups after treatment,the bloodβ-hCG decline rate and bad reaction were compared. Result:The cure rate of patients in the experimental group was better than the control group,mass narrowing>30%more than the control group,the average hospitalization time and incidence rate of adverse reaction was less than in the control group, these indicators between the two groups had statistical significance(P<0.05);the bloodβ-hCG was decreased compared with before treatment in the two groups of patients after treatment,the experimental group decreased more obviously(P<0.05). Conclusion:The ultrasound guided methotrexate local injection in the treatment of ectopic pregnancy has achieved good effect,and can reduce adverse reaction for patients.