ICU感染性休克病死危险因素及相应的临床治疗措施分析

摘要

Objective: To analyze the fatality rate caused by septic shock, risk factors for fatality and the corresponding clinical therapeutic measures in ICU.Method: Ninety-six cases of patients with septic shock were analyzed retrospectively, and the risk factors for fatality of patients were analyzed with single-factor and multiple-factor Logistic regression analysis method.Result: The case fatality rate of the 96 cases of patients was 57.29%; The results of single-factor analysis showed that the APACHEⅡ score, age, number of SIRS, blood infection, 24 h urinary amount, mean arterial pressure and albumin and the number of MODS of the survival group and the fatality group in the patients with septic shock had significant difference (P<0.05). The multiple-factor Logistic regression analysis showed that Albumin, number of SIRS, APACHE Ⅱ score and the number of MODS were the risk factors causing fatality of patients with septic shock in the ICU.Conclusion: For patients with septic shock in ICU, active control measures to inflammatory responses and comprehensive treatment on the basis of pathogenesis removal can help reduce the fatality rate during treatment.%目的：对ICU感染性休克病死率、病死危险因素与相应临床治疗措施进行分析。方法：对96例感染性休克患者展开回顾性分析，利用单因素与多因素Logistic回归分析方法对患者病死危险因素展开分析。结果：96例患者病死率为57.29%；单因素分析结果显示，在感染性休克患者中，存活组与死亡组在APACHEⅡ评分、年龄、SIRS数目、血液感染、平均动脉压及白蛋白、24 h尿量与MODS数目8个因素差异有统计学意义（P<0.05）；多因素Logistic回归分析结果表明，白蛋白、SIRS数目、APACHEⅡ评分与MODS数目是导致ICU感染性休克患者病死的独立危险因素。结论：在对ICU感染性休克展开治疗时，对炎症反应进行积极调控，以去除病因为基础展开综合治疗，可有效降低该疾病病死率。