伴有紧张性症状的女性双相情感障碍的临床研究

摘要

Objective:To investigate the clinical characteristics of bipolar disorder in women with nervous symptoms.Method:The clinical data of 30 patients with nervous symptoms at the time of admission,at discharge in accordance with the ICD -10 nervous type schizophrenia(the group A) and 30 patients with bipolar disorder(the group B) were retrospectively analyzed.Result:The disease stage of group A and group B were (37.9±17.7)d,(18.0±13.4)d; admission diagnosis coincidence rate were 93.3%,60.0% respectively,the differences were statistically significant (P<0.05).The clinical phenomenon of comparison:the group B acute onset,before the disease affected by stress factors easy hypomania,mostly when accompanied by nervous symptoms "as a state","mannerisms" dramatic behavior, within 1 week of treatment could relieve and the reaction was sensitive to the group A.BPRS assessment after symptom remission showed that the scores of "activated","anxiety depression" factors in group A were higher than those in group B(P<0.05)."the lack of vitality","hostile suspicion" factor and “thought obstacle” factor score in group A were significantly higher than those in group A(P<0.05).Conclusion:Nervous symptoms associated with schizophrenia and bipolar disorders,but the differences are statistically significant in the onset of both forms,the impact of stress, personality characteristics and treatment response of the two groups.And after symptom remission,the "lack of vitality","hostile suspicion "" thought disorder " of group A are significantly different from the excitement,anxiety and other emotional characteristics of group B.%目的：探讨伴紧张症状女性双相情感障碍的临床特点。方法：回顾性分析入院时伴紧张症状、出院时符合ICD-10的紧张型精神分裂症（A组）与双相情感障碍症（B组）各30例患者的临床资料。结果：A、B两组患者病期分别为（37.9±17.7）d、（18.0±13.4）d；入院诊断符合率分别为93.3%、60.0%，差异均有统计学意义（P<0.05）。临床现象的比较：B组起病急，病前受应激因素影响易轻躁狂，伴紧张症状时多呈“作态”、“装相”戏剧化行为，治疗1周内可缓解且反应敏感于A组。A组患者症状缓解后的BPRS评定显示“激活性”因子、“焦虑忧郁”因子分值均明显高于B组（P<0.05），B组患者症状缓解后的BPRS评定显示“缺乏活力”因子，“敌对猜疑”因子，“思维障碍”因子分值均明显高于A组（P<0.05）。结论：紧张性症状与精神分裂症、双相情感障碍有关，但两者的起病形式、应激影响、性格特点以及治疗反应性差异显著，且症状缓解后A组的“缺乏活力”、“敌对猜疑”、“思维障碍”明显区别于B组的兴奋、焦虑等情绪化特点。