Stathmin与胃肠道肿瘤关系的研究进展

摘要

Stathmin expresses high in many malignant tumor cells,The proliferation,differentiation,and other biological behavior changes of cells can be activated by stathmin protein. Overexpression of Stathmin may affect the efficacy of anti-microtubule chemotherapeutic agents. The level of stathmin expression in gastrointestinal tumors is also high,The study of stathmin has important significance for the treatment of tumors.%Stathmin在多种恶性肿瘤细胞中都高水平表达，Stathmin蛋白可以改变细胞的增殖、分化、活性等生物学行为。Stathmin的过表达可影响抗微管化学治疗药物的疗效。Stathmin在胃肠道肿瘤中也有高水平表达，针对Stathmin的研究对肿瘤的治疗有重要的意义。