hs-CRP联合WBC对儿童哮喘的临床诊断价值分析

摘要

目的：研究hs-CRP联合WBC对儿童哮喘的临床诊断价值。方法：选取2013年5月-2015年3月本院诊断为支气管哮喘的81例患儿为观察组，并选择同期健康儿童81例作为对照组。比较两组治疗前后的hs-CRP水平和WBC计数变化，并将阳性结果与最终细菌感染的患儿的结果差异进行比较分析。结果：治疗前观察组的hs-CRP水平和WBC计数均显著高于对照组。治疗后观察组的hs-CRP水平和WBC计数均显著低于治疗前，差异均有统计学意义（P<0.05）。hs-CRP阳性共53例，细菌感染总检出率为94.59%（35/37），非细菌感染中阳性18例，误诊率为40.91%（18/44）；WBC阳性共41例，总检出率为63.41%（26/41），非细菌感染者中WBC阳性15例，误诊率为34.09%（15/44），两者比较差异有统计学意义（P<0.05）。结论：hs-CRP水平和WBC计数对于儿童哮喘的诊断有着密切的关系，在急性发作时，hs-CRP水平和WBC计数均升高，不仅能够作为患儿发作的敏感标志物，还是判断患儿疗效的重要指标。%Objective: To study the clinical diagnostic value of the hs-CRP combined with the WBC in childhood asthma.Method: 81 cases in our hospital who diagnosed with bronchial asthma were selected from May 2013 to March 2015 as the observation group, and 81 cases healthy children were selected in the same period as the control group. Before and after treatment,the hs-CRP level and WBC count change,the positive results and eventually bacterial infection children of two groups were compared.Result: Before treatment,the hs-CRP levels and the WBC count of the observation group were significantly higher than the control group; after treatment, the hs-CRP levels and the WBC count of observation group were significantly lower than before treatment,the differences were statistically significant (P<0.05).A total of hs-CRP positive were 53 cases, bacterial infections overall detection rate was 94.59%(35/37),the positive in non-bacterial infection were 18 cases, the misdiagnosis rate was 40.91%(18/44); a total of the WBC positive were 41 cases, the overall detection rate was 63.41%(26/41), the positive in non-bacteria infection were 15 cases, the misdiagnosis rate was 34.09%(15/44),the differences were statistically significant(P<0.05).Conclusion: hs CRP level and WBC count for the diagnosis of childhood asthma has the close relation.In acute onset, hs-CRP level and WBC count are higher, not only as a sensitive marker for children, but also the important index of judging curative effect in children with.