幽门螺杆菌感染致消化性溃疡的临床特点及干预对策

摘要

Objective:To summarize clinical characteristics and intervention measures of peptic ulcer paitents infected by helicobacter pylori,to improve the clinical treatment of these patients,reduce the relapse rate,reduce the relapse rate.Method:240 paitents with peptic ulcer caused by helicobacter pylori infection were selected from September 2009 to August 2011,their clinical characteristics and intervention measures were summarized. 240 paitents with peptic ulcer caused by Helicobacter pylori infection were selected from September 2012 to August 2014,they were randomly divided into control group and observation group,120 cases in each group,the control group was treated with conventional therapy treatment,the observation group was treated by intervening measure on the basis of conventional therapy,then the recent clinical results and long-term recurrence rate were compared between two groups. Result:The proportion of males caused by helicobacter pylori infection in patients with peptic ulcer disease higher than women;different ages compared to the proportion,the population aged 20-50 years was significantly higher than others,duodenal ulcer patients were significantly higher than gastric ulcer patients,compared all the indicators,the differences were statistically significant(P<0.05).Two groups of a short-term effect were observed,the difference was not statistically significant(P>0.05);but the long-term recurrence rate of observation group was significantly lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion:Patients with peptic ulcer caused by helicobacter pylori infection with a more specific clinical features,targeted interventions take countermeasures against its features,which can effectively reduce the relapse rate of patients and improve treatment levels.%目的：总结幽门螺杆菌感染致消化性溃疡患者的临床特点，探讨干预措施对此类患者治疗过程中的作用，以提高此类患者的临床治疗效果，降低复发率。方法：回顾性分析本院2009年9月-2011年8月间收治的240例幽门螺杆菌感染致消化性溃疡患者的临床资料，总结此类患者的临床特点，根据此类患者的临床特点，制定此类患者治疗过程中可以采取的干预对策，并再次筛选本院2012年9月-2014年8月期间收治的幽门螺杆菌感染致消化性溃疡患者240例，随机分为对照组和观察组，每组各120例患者。对照组患者采用常规治疗方法治疗，观察组在对照组常规治疗的基础上，再予以干预措施，比较两组患者近期临床治疗效果及远期复发率，评价干预对策对幽门螺杆菌感染致消化性溃疡患者治疗的影响。结果：幽门螺杆菌感染致消化性溃疡男患者比例高于女患者；不同年龄段比较，20~50岁中青年人群比例明显高于其他人群；十二指肠溃疡患者明显高于胃溃疡患者，上述指标比较，差异均具有统计学意义（P<0.05）。对照组患者和观察组患者在近期疗效上比较，差异无统计学意义（P>0.05），但在远期复发率比较，观察组明显低于对照组患者，差异具有统计学意义（P<0.05）。结论：幽门螺杆菌感染致消化性溃疡患者具有较为特异的临床特征，针对其特征采取针对性地干预对策，可有效降低患者的复发率，提高治疗水平。