三维适形放疗应用于非小细胞肺癌的临床效果分析

摘要

Objective:To study the clinical effect of 3DCRT in the treatment of NSCLC.Method:From January 2011 to July 2015 in our hospital 60 NSCLC patients were selected.The patients were randomly divided into the observation group and the control group,30 cases in each group.Both of groups adopted TP therapy,the control group was only given the conventional chemotherapy,the observation group was given 3DCRT.Result:The short-term effective rate of the observation group(86.7%) was significantly higher than that of the control group (56.7%)(P<0.05).The single score and total score of life quality of the observation group was higher than that of control group(P<0.05).The observation group had 3 cases of anemia,4 cases of declining leukocyte,3 cases of declining thrombocytopenia,1 case of nausea and vomiting and 2 cases of alopecia.The incidence rates of the observation group were lower than those of control group(P<0.05).The incidence rate of abnormal hepatic and renal function of two groups was not significantly difference(P>0.05).Conclusion:3DCRT has an obvious effect in NSCLC patients at middle and advanced stage,fewer toxic and side effect.The patient’s condition combined with chemotherapy can be regarded as the first-line therapy in NSCLC.%目的：探讨三维适形放疗应用于非小细胞肺癌的临床效果。方法：选取2011年1月-2015年7月本院收治的60例非小细胞肺癌患者为研究对象，将其按照随机数字表法分为观察组与对照组，各30例，两组均采用TP方案化疗，在此基础上对照组采用常规化疗，观察组采用三维适形放疗。结果：观察组近期有效率为86.7%，对照组为56.7%，观察组高于对照组，差异有统计学意义（P<0.05）。观察组生存质量各维度评分和总分均高于对照组，差异均有统计学意义（P<0.05）。观察组发生贫血3例，白细胞下降4例，血小板减少3例，恶心呕吐1例，脱发2例，发生率均显著低于对照组（P<0.05），两组肝肾功能异常发生率比较差异无统计学意义（P>0.05）。结论：三维适形放疗对中晚期NSCLC患者效果显著，且毒副反应可耐受，可根据患者实际情况与化疗相结合，作为NSCLC的一线治疗方案。