首页> 外国专利> EML4-ALK ALK Method for providing the information for selecting the drugs for treating EML4-ALK positive non-small cell lung cancer and compositions for treating non-small cell lung cancer resistant to ALK inhibitors

EML4-ALK ALK Method for providing the information for selecting the drugs for treating EML4-ALK positive non-small cell lung cancer and compositions for treating non-small cell lung cancer resistant to ALK inhibitors

机译:用于提供用于治疗EML4-ALK阳性非小细胞肺癌的药物的信息的EML4-ALK ALK方法,用于治疗耐碱抑制剂的非小细胞肺癌的组合物

摘要

The present invention relates to a method for providing information for selecting a treatment drug for EML4-ALK-positive non-small cell lung cancer patients and a composition for treating ALK inhibitor-resistant non-small cell lung cancer. A method for providing information for selecting a treatment drug for EML4-ALK-positive non-small cell lung cancer patients, comprising measuring the expression level and methylation level, and a deoxycytidine analog or a pharmaceutically acceptable salt thereof as an active ingredient It relates to a composition for treating non-small cell lung cancer that has acquired resistance to an ALK inhibitor.
机译:本发明涉及一种用于提供用于为EML4-ALK阳性非小细胞肺癌患者选择治疗药物的信息的方法和用于治疗ALK抑制剂的非小细胞肺癌的组合物。 一种提供用于为EML4-ALK阳性非小细胞肺癌患者选择治疗药物的信息的方法,包括测量表达水平和甲基化水平,以及作为其涉及的活性成分的脱氧胞苷类似物或其药学上可接受的盐 一种用于治疗非小细胞肺癌的组合物,其具有对ALK抑制剂的抗性。

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