羟乙基淀粉氯化钠130/0.4联合呋塞米治疗ICU严重水肿的疗效观察

摘要

Objective To observe the edema variation in patients in ICU with severity edema treated with hydroxyethyl starches130/0.4(HES 130/0.4)/furosemide. Methods Forty four patients in ICU with severity edema in the Af iliated Hospital of Guilin medical col ege were enrol ed, and they were treated with isotonic Na chloride/furosemide and HES 130/0.4)/furosemide sequencely. A self-control study was conducted. Results The urinary volume,urinary sodium and urinary potassium of patients during HES 130/0.4/furosemide infusion were more than those of patients during isotonic Na chloride/furosemide infusion, especial y urinary volume and urinary potassium (P<0.05). Conclusion It was ef ective that treating patients in ICU with severity edema with HES 130/0.4/furosemide, while electrolyte disturbances need to be monitored and prevented.%目的：观察羟乙基淀粉氯化钠130/0.4联合呋塞米对ICU严重水肿患者的利尿作用。方法采取自身对照的方法对2011年1月~2012年12月在桂林医学院附属医院ICU住院治疗的54例伴全身严重水肿的危重患者先后给予生理盐水联合呋塞米、羟乙基淀粉氯化钠130/0.4联合呋塞米进行利尿治疗，观察比较两种利尿方法的效果。结果患者使用羟乙基淀粉氯化钠130/0.4联合呋塞米时的24h尿量、尿钠及尿钾多于生理盐水联合呋塞米时，24h尿量及尿钾尤为显著（P＜0.05）。结论羟乙基淀粉氯化钠130/0.4联合呋塞米能快速、有效的治疗ICU严重水肿患者，但需及时监测和防止电解质紊乱。