探讨多囊卵巢综合症与青春期功血相关性

摘要

objective by analyzing the adolescent menstrual disorder in patients with polycystic ovary syndrome, adolescent dysfunctional uter-ine bleeding () function and clinical data and laboratory results of normal women, and give an early comprehensive treatment in patients with poly-cystic ovary syndrome and intervention, and expect to reduce the infertility and forward of the metabolic syndrome and endometrial malignant lesions. Methods choose 90 cases of menstrual disorder patients and the clinical data of 30 cases of normal female age, menstrual cycle and period of days in all subjects, sex hormone and testosterone classification, oral glucose tolerance and insulin results, waist hip ratio, small vaginal ultrasound measure-ment of ovarian follicle number and volume, etc.The results were analyzed.Results (1) 55.55% adolescent menstrual disorders in patients with polycystic ovary syndrome and 34.44% for the blood;(2) the three groups of insulin resistance in patients with polycystic ovary syndrome group in-creased significantly (t =5.48, P <0.05), adolescence work times blood group, normal control group at least;(3) patients with polycystic ovary syndrome group significantly higher than the level of serum free testosterone and sex hormone binding globulin (SHBG) is lower than the normal con-trol group (t were 5.21, 3.76, P <0.05), FSH and E due to the rise of LH is often lower than normal;(4) group of patients with polycystic ovary syndrome type B ultrasound examination reealed bilateral or unilateral ovarian volume increased obviously in the work of blood group, small follicle increased (t =10.02, p <0.05).Conclusion part of the diagnosis of polycystic ovary syndrome in adolescent patients with function, blood work can be early performance of PCOS, attaches great importance to the clinical diagnosis and rational treatment of its positive or early prevention and fol-low-up, hope to be able to stop the part for the development of PCOS patients.%目的：通过分析青春期月经失调患者中多囊卵巢综合征、青春期功能失调性子宫出血（功血）和正常女性的临床资料及实验室检查结果，并对卵巢多囊综合症患者给予早期综合治疗及干预，期望减少不孕及远期的代谢综合症及子宫内膜恶性病变。方法选择90例月经失调患者和30例同龄正常女性的临床资料，对所有受试者的月经周期与经期天数、性激素及雄激素分类、口服葡萄糖耐量和胰岛素检查结果、腰臀围比、阴道B超测量卵巢小卵泡数及体积等结果进行分析。结果①青春期月经失调患者中55．55％为多囊卵巢综合征，34．44％为功血；②3组患者中多囊卵巢综合征组胰岛素抵抗者明显增多（t＝5．48，P＜0．05），青春期功血组次之，正常对照组最少；③多囊卵巢综合征组患者血清游离睾酮水平明显高于和性激素结合球蛋白低于正常对照组（t分别为5．21、3．76，均P＜0．05），FSH及E由于LH的升高常较正常值低；④多囊卵巢综合征组患者B型超声检查示双侧（或单侧）卵巢体积较功血组明显增大，小卵泡增多（t＝10．02，p＜0．05）。结论青春期功血患者中部分诊断为多囊卵巢综合症，功血可能是PCOS的早期表现，重视其临床诊断及对其积极合理的治疗或早期的预防及随诊，希望能阻止部分患者发展为PCOS。