血清降钙素原对社区获得性肺炎病原学检测及治疗的临床价值

摘要

Objective: To study the clinical value of serum procalcitonin (PCT) on the etiology detection and therapy of community acquired pneumonia(CAP). Methods: 157 patients with CAP in our hospital were involved and the serum PCT, bacterial culture were carried out in all the cases. The relationships between serum PCT and bacterial culture and severe pneumonia were analyzed. Results: The positive rate of germiculture in the group which PCT>0.5 ng/ml was significantly higher than yhat in the group which PCT<0.5ng/ml (67.4% & 29.2%,P < 0.05).The PCT in the severe pneumonia group was significantly higher than that in the no severe pneumonia group (2.2 ±0.6 ng/ml &0.78±0.2 ng/ml,P < 0.05). The positive rate of germiculture in the severe pneumonia group was significantly higher than that in the no severe pneumonia group(76.1% & 41.4%,P < 0.05). Conclusion: Serum PCT can help to identify the infection, to direct the therapy of antibiotics, to evaluate the severity, and to predict the prognosis of CAP.%目的：研究血清降钙素原（PCT）在社区获得性肺炎（CAP）病原学检测及治疗中的临床意义。方法：我院确诊CAP的病人共157例，所有病人入组时全部进行PCT检测以及细菌培养，分析血清PCT与细菌培养结果及与重症肺炎的关系。结果：PCT ＞0．5 ng/ml 组细菌培养阳性率明显高于 PCT＜0．5 ng/ml 组（67．4％＆29．2％，P ＜0．05）；重症肺炎组 PCT 值明显高于非重症肺炎组（2．2±0．6 ng/ml ＆0．78±0．2 ng/ml，P ＜0．05）；重症肺炎组细菌培养阳性率明显高于非重症肺炎组（76．1％＆41．4％，P ＜0．05）。结论：血清 PCT水平有助于判断CAP的感染性质和指导抗生素的治疗，有利于评估病情的严重程度及预测预后。