鼻渊舒口服液与西药治疗慢性鼻窦炎的临床疗效及安全性对比分析

摘要

目的：研究并对比鼻渊舒口服液与西药治疗慢性鼻窦炎的临床疗效及安全性。方法2013年1～12月该院门诊就诊的慢性鼻窦炎患者共186例。以数字法随机分成观察组（93例）和对照组（93例）。观察组患者使用鼻渊舒口服液进行治疗；对照组患者则使用西药进行治疗。对两组患者进行为期40 d的治疗后，通过患者的治疗效果、用药后并发症以及治疗后的复发情况来比较两组患者的治疗情况。结果通过40 d的治疗后发现观察组和对照组的临床疗效都比较好，两组的治疗效果差异无统计学意义（P＞0．05）。在治疗中因为用药导致全身多个系统出现并发症，观察组的总并发症发生率为4．3％，对照组30．11％，两组恶心呕吐、头晕目眩、全身乏力及总并发症发生率差异均有统计学意义（均 P＜0．05）。在治疗结束后两组患者均出现不同程度上的病情复发，观察组有8例（8．60％）患者出现复发，而对照组中则有32例（34．41％）患者出现复发，两组复发率差异有统计学意义（ P＜0．05）。结论使用鼻渊舒口服液对慢性鼻窦炎进行治疗后发现治疗结果良好，并发症少，值得在临床上广泛推广。%Objective To investigate and compare the clinical efficacy and safety of Biyuanshu Oral Liquid and Western medicines in the treatment of chronic sinusitis .Methods A total of 186 patients with chronic sinusitis visi‐ted the outpatient department of our hospital from January 2013 to December 2013 were randomized into the observa‐tion group(93 cases) and the control group(93 cases) with the digital method .The observation group received Biyuanshu Oral Liquid ,while the control group was given Western medicines .The therapeutic effects ,drug‐induced complications and recurrence after 40 d treatment were compared between two groups .Results The curative effects after 40 d treatment in the both two groups were better without statistical difference between them (P>0 .05) .The complications of multiple systems were caused by drugs in the treatment process ,the total occurrence rate of compli‐cations in the observation group was 4 .3% ,which was lower than 30 .11% in the control group ,and the difference was statistically significant(P<0 .05) .Nausea and vomiting ,dizziness ,hypodynamia and the total occurrence rate of complications had statistical differences between the two groups (P<0 .05) .The different degrees of recurrence after treatment occurred in the two groups .8 cases of recurrence were in the observation group and 32 cases of recurrence were in the control group ,the difference in the recurrence rate between the two groups had statistical significance (P<0 .05) .Conclusion Biyuanshu Oral Liquid has better effect and less complications in treating chronic sinusitis and is worthy of being widely promoted in clinic .