健康体检人群高血压前期与糖脂代谢异常状况研究

摘要

Objective To study the state of prehypertension and disorder of glucolipide metabolism (DGM ) in health examina‐tion population .Methods A total of 200 subjects ,receiving health examination in this hospital from January 2014 to June 2015 , were enrolled .Blood pressure ,body mass index ,serum triacylglycerol(TG) ,total cholesterol(TC) ,high density lipoprotein choles‐terol(HDL‐C) ,low density lipoprotein cholesterol(LDL‐C) ,fasting blood glucose ,uric acid and other indicators were compared .Re‐sults Among all subjects ,54 cases were with prehypertension ,accounting for 27 .00% ,and the rate of male patients was signifi‐cantly higher than female patients(P<0 .05) .In all patients ,the proportion of subjects of 25-45 years old was significantly more than subjects with normal blood pressure and patients with high blood pressure (P<0 .05) .HDL‐C levels in patients with prehyper‐tension was obviously lower than subjects with normal blood pressure and higher than patients with hypertension ,and other bio‐chemical indicators were significantly higher than subjects with normal blood pressure and lower than patients with high blood pres‐sure(P<0 .05) .Pure lipid metabolic abnormalities ,hypertriglyceridemia ,hypercholesteremia and mixed hyperlipidemia were charac‐terized by men more than women (P< 0 .05) .Subjects of all ages were with significant difference of DGM detection rates (P<0 .05) .Conclusion The onset age of prehypertension and DGM in health examination population might be younger ,and the propor‐tion of male could be higher .Subjects with hypertension and DGM could be with more cardiovascular risk factors .%目的：研究健康体检人群高血压前期与血糖血脂代谢异常状况。方法选择2014年1月至2015年6月在该院接受健康体检者200例，测量血压、体质量指数，及血清三酰甘油（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL‐C）、低密度脂蛋白胆固醇（LDL‐C ）、空腹血糖、尿酸等指标；比较不同性别、年龄段人群高血压检出率和糖脂代谢异常检出率，比较合并及不合并糖脂代谢异常高血压患者各指标水平。结果共检出高血压前期患者54例，检出率为27．00％，且男性患者所占比例高于女性（P＜0．05）。高血压前期患者中，25～＜45岁者所占比例高于血压正常者和高血压患者（P＜0．05）。高血压前期患者 HDL‐C水平低于血压正常者且高于高血压患者，其他血清指标水平高于血压正常者且低于高血压患者（P＜0．05）。单纯脂代谢异常、高TG血症、高TC血症及混合型高血脂症患者中，男性所占比例高于女性（P＜0．05），各年龄段人群糖脂代谢异常检出率比较差异有统计学意义（P＜0．05）。高血压前期患者糖脂代谢异常检出率高于血压正常者且低于高血压患者（P＜0．05）。合并糖脂代谢异常高血压前期患者年龄、舒张压、TG、TC、LDL‐C等指标水平高于不合并者，HDL‐C水平低于不合并者（P＜0．05）。结论健康体检人群高血压前期和糖脂代谢异常发病呈年轻化趋势，且男性所占比例较大，合并糖脂代谢异常高血压前期患者存在更多的心脑血管疾病危险因素。