坦索罗辛及前列通片联合非那雄胺治疗老年ⅢB型前列腺炎的临床观察

摘要

[Objective] To observe the clinical efficacy of tamsulosin and qianlietong tablets combined with finasteride on the elderly patients with ⅢB chronic prostaticis(CP). [Methods] 125 cases of the elderly patients with IIIB prostatitis were randomly divided into 3 groups. 44 cases of the treatment group was treated with tamsulosin and qianlietong tablets combined with finasteride, 40 cases of control group 1 was treated with tamsulosin combined with finasteride, 4t cases of control group2 was treated with qianlietong tablets combined with finasteride. Changes of N1H-CPSI score, IPSS score, QLS score, PS score, USS score, EPS WBC count, SPL and other indicators of the situation were compared among the three groups pre-treatment and after the treatment of 4 weeks, 8 weeks and 12 weeks. The results were statistically analyzed. [Results] In the treatment group, 11 cases clinically cured, 17 cases clinically significantly effective, 12 cases effective, 4 cases ineffective, the total effective rate was 90.91%.In the control group 1, 6 cases clinically cured, 8 cases clinically significantly effective, 16 cases effective, 10 cases ineffective, the total effective rate was 75%. In the control group2, 5 cases clinically cured, 9 cases clinically significantly effective, 15 cases effective. 12 cases ineffective, the total effective rate was 70.73%. Compared with the control group 1 and the control group2, the improvement of the treatment group in NIH—CPSl,IPSS,QLS,USS,PS was significantly different. There were no significant differences in the indicators between the control group 1 and the control group2. [Conclusion] It demonstrates a significant effect of tamsulosin and qianlietong tablets combined with finasteride therapy for the elderly patients with type ⅢB prostatitis.%[目的]观察坦索罗辛及前列通片联合非那雄胺治疗老年ⅢB型慢性前列腺炎(CP)的临床疗效.[方法]将老年ⅢB型CP患者125例随机分为3组,治疗姐44例应用坦索罗辛及前列通片联合非那雄胺,对照1组40例应用坦索罗辛联合非那雄胺,对照2组41例应用前列通片联合非那雄胺,比较3组治疗前和治疗4、8、12周后的CP症状评分(NIH-CPSI)、国际前列腺症状评分(IPSS)、生活质量评分(QLS)、疼痛症状评分(PS)、排尿症状评分(USS)以及前列腺液(EPS)中WBC计数、卵磷脂小体(SPL)等指标的情况.[结果]总有效率治疗组90.91％;对照1组75.00％;对照2组70.73％.治疗组在改善患者NIH-CPSI、IPSS、QLS、USS、PS及EPS指标等方面与对照1组、对照2组比较,差异有统计学意义(P＜0.05)；对照1组与对照2组间各项指标比较,差异无统计学意义(P＞0.05).[结论]坦索罗辛及前列通片联合非那雄胺治疗老年ⅢB型CP疗效良好.