[目的]探讨介入栓塞治疗原发性肝癌合并肝动静脉瘘(AVS)的疗效.[方法]按入组编号,将36例原发性肝癌合并肝动动静脉瘘患者随机分为观察组及对照组,每组各18例,观察组采取先堵动静脉瘘口后再行化疗栓塞,对照组采取先行化疗栓塞后再堵动静脉瘘口,对比两组患者动静脉瘘口闭塞程度、肿瘤治疗客观疗效及不良反应情况.[结果]观察组动静脉瘘口闭塞程度明显优于对照组,差异有统计学意义(P＜0.05)；且肿瘤治疗客观疗效观察组明显优于对照组,两组病灶变化相比亦有统计学意义(P＜0.05),；而不良反应观察组则少于对照组,两组相比有显著性差异(P＜0.05).[结论]对于原发性肝癌合并AVS的介入治疗,可先予明胶海绵颗粒或PVA颗粒堵塞动静脉瘘口再行动脉灌注化疗栓塞治疗,能提高肿瘤治疗疗效,还可减轻不良反应,值得临床推广应用.%[Objective] To investigate the strategies and the efficacy of intervention treating with primary hepatocellular carcinoma combined with hepatic arteriovenous fistula. [Methods] 36 cases of primary hepatocellular carcinoma combined with hepatic arteriovenous fistula were divided into control group and observation group, according to numbers, and each group had 18 cases. The observation group taking the first block after fistula embolization while the control group taking first block after fistula embolization. Compare the blocking, objective response and adverse reactions of the two groups. [Results] The block fistula in the observation group was better than the control group, there were statistically significant differences; objective efficacy in the observation group was higher than the control group, and the two groups had statistically significant changes of lesion; the adverse reactions in the observation group were less than the control group. [Conclusion] For the intervention of primary hepatocellular carcinoma combined with hepatic arteriovenous fistula, it could be blocking the fistula and then take embolization therapy; the strategy can not only improve the efficacy, but also reduce adverse reactions, which should be widely applied in clinic.
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