川崎病患儿热退后应用黄芪注射液的疗效分析

摘要

[目的]评价黄芪注射液辅助治疗热退后川崎病(Kawasaki disease,KD)患儿的临床疗效.[方法]将82例经治疗热退后的KD患儿随机分成两组.对照组40例,应用阿司匹林(Asprin,ASA)3mg/(kg·d),治疗组42例,在对照组基础上加用黄芪注射液,14d为1疗程,共1疗程.[结果]治疗组治疗后C反应蛋白(CRP)、血小板(PLT)、血沉(ESR)较对照组下降明显(P＜0.05),冠状动脉病变(Coronary artery lesions,CAL)发生率明显降低(P＜0.05)；两组临床总疗效比较,治疗组优于对照组(P＜0.05).[结论]黄芪注射液配合治疗热退后的KD患儿,可缩短病程,提高临床疗效,降低CAL的发生率并且有较好的安全性.%[Objective] To observe the cure effect of Astragalus Injecta treating children of KD after fever in assistance. [Method] Randomly divide 82 cases into 2 groups; control group 40 cases take Asprin, the treatment group 42, added with Astragalus Injecta on the basis of control group; 14d as a course. [Result] In treatment group, CRP, PLT and ESR reduced much more than control one, CAI decreased a lot; comparison of clinical cure effect of both groups showed the treatment group was better than control one. [Conclusion] The Astragalus Injecta in combination treating children of KD after fever can ihorten disease course, improve clinical effect and reduce CAI occurrence rate with good safety.