病毒性脑炎患儿血小板参数的动态改变

摘要

Objective To explore the clinical value of platelet parameters including platelet count (PLT) , mean platelet volume ( MPV) , platelet distribution width ( PDW) and platelet - large cell ratio ( P - LCR) in children with viral encephalitis. Methods PLT, PDW, MPV and P - LCR were detected in 28 children with viral encephalitis in acute stage and recovery stage (viral encephalitis group ) and 30 healthy children ( control group ). Results MPV, PDW and P — LCR were significantly higher in the acute stage of viral encephalitis than in the recovery stage and healthy controls (P <0.01). There were no significant differences for MPV , PDW and P - LCR between recovery stage of viral encepha -litis and control group ( P > 0. 05 ). PLT showed no significant difference among the acute and recovery phase of viral en — cephalitis and control group (P >0.05 ). Conclusion The detection of platelet parameters is helpful in assessing the se -verity of disease and evaluating the efficacy of treatment for viral encephalitis in children .%目的 探讨血小板计数(PLT)、平均血小板体积(MPV)、血小板分布宽度(PDW) 和大血小板比例(P-LCR)在儿童病毒性脑炎(简称病脑)中的动态变化及其临床意义.方法 分别检测28例病脑急性期和恢复期患儿(病脑组)以及30例健康儿童(对照组)的PLT、MPV、PDW和P-LCR,并进行比较分析.结果 病脑急性期MPV、PDW、P-LCR水平高于病脑恢复期和对照组(P<0.01);病脑恢复期MPV、PDW、P-LCR水平与对照组差异无统计学意义(P>0.05); PLT在病脑急性期、恢复期及对照组间差异均无统计学意义(P>0.05).结论 血小板参数的检测有助于儿童病脑的病情评估和疗效监测.