胸腔镜下肺段切除与肺叶切除治疗早期肺癌临床疗效评估

摘要

目的 评估并比较胸腔镜下肺段切除术与肺叶切除术治疗早期肺癌的术后近期疗效.方法 回顾分析35例早期肺癌手术患者,分为肺叶组(n=17)和肺段组(n=18).肺叶组行胸腔镜肺叶切除术,肺段组行胸腔镜肺段切除术.比较2组手术时间、术中出血量、住院时间等指标的差异;选取用力肺活量(FVC)、第1秒用力呼气量(FEV1)作为肺功能的评估指标,随访1年,比较2组患者肺功能改善情况.结果 2组患者住院时间、术中出血量差异无统计学意义(P＞0.05);与肺叶组相比,肺段组手术时间更长;所有患者随访1年,肺段组患者肺功能各项指标均优于肺叶组(P＜0.05).结论 胸腔镜下肺段切除术与肺叶切除术治疗早期肺癌术后近期内均安全有效,肺段切除术更有利于保护患者的肺功能.%Objective To compare the early clinical efficacy of video-assisted thoracoscopic segmentectomy and lobectomy for the treatment of early-stage lung cancer.Methods Retrospective analysis was performed using clinical data from 35 lung cancer patients at early stage.They were divided into a lobectomy group (n =17) and a segmentectomy group (n =18).The lobectomy group underwent video-assisted thoracoscopic lobectomy,while the segmentectomy group received video-assisted thoracoscopic segmentectomy.Then,both groups were compared for the operation time,intra-operative blood loss,and hospitalization stay.All patients were follow-up visited for one year to evaluate their pulmonary function.Results There was no significant difference in intra-operative blood loss and hospitalization stay between the two groups (P ＞ 0.05).The lobectomy group required longer operation time than the segmentectomy group.One year after operation,patients in the segmentectomy group showed better pulmonary function than those in the lobectomy group (P ＜ 0.05).Conclusions Both video-assisted thoracoscopic segmentectomy and S lobectomy are safe and effective in the treatment of early-stage lung cancer in the short term.Video-assisted thoracoscopic segmentectomy is more beneficial to protect postoperative pulmonary function.