3种不同的首次高压氧治疗压力在急性一氧化碳中毒中的疗效观察

摘要

目的：对比3种不同的首次高压氧（HBO）治疗压力在急性一氧化碳中毒（ACOP）中的疗效，为临床采用安全有效的首次治疗压力提供参考。方法选取2012年1月1日－2015年12月31日300例急性一氧化碳中毒患者，随机分为3组，A 组100例采用2．3ATA 首次治疗压力（新疆维吾尔自治区人民医院），B 组100例采用2．5ATA首次治疗压力（新疆昌吉市第一人民医院），C 组100例（新疆医科大学第六附属医院）采用2．8ATA 首次治疗压力。比较3组患者的促醒时间、迟发性脑病（DEACMP）发生率及治愈率。结果C 组促醒时间与 A、B 组比较差异均有统计学意义（P ＜0．01），A 组促醒时间与 B 组比较差异无统计学意义（P ＞0．05）。C 组 DEACMP 发生率与 A、B 组比较差异均有统计学意义（P ＜0．01），A 组 DEACMP 发生率与 B 组比较差异有统计学意义（P ＜0．01）。C 组治愈率与 A、B 组比较差异均有统计学意义（P ＜0．01），A 组治愈率与 B 组比较差异有统计学意义（P＜0．01）。结论2．8ATA 首次治疗压力可缩短中重度 ACOP 的促醒时间，减少 DEACMP 的发生，提高治愈率，临床应推广应用。%Objective To compare clinical effect of 3 different initial pressure of hyperbaric oxygen therapy in acute carbon monoxide poisoning,the safest and most effective treatment for the first time the pressure reference.Methods From 300 patients with acute carbon monoxide poisoning were received hyperbaric ox-ygen therapy January 2012 to December 2015.A group of 100 patients with 2.3ATA treatment for pressure (the Xinjiang Uygur Autonomous Region people′s Hospital),B group of 100 patients with 2.5ATA for the first time in treatment of stress (the First People's Hospital of Xinjiang Changji),100 cases in C group (the Sixth Affiliated Hospital of Xinjiang Medical University)for the first time 2.8ATA treatment pres-sure.Compared with 3 groups of awaking time,delayed encephalopathy incidence and recovery rates.Re-sults Compared to group C,the awaking time of group A and group B increased significantly (P <0.01), A group of awaking time and B group had no significant difference (P >0.05).C group delayed brain dis-ease incidence and a,B group,the differences were statistically significant (P <0.01).A group late onset encephalopathy occurred rate and B group difference has statistical significance (P <0.01).C group,the cure rate and a,B group,the differences were statistically significant (P <0.01),A group cure rate and B group difference was statistically significant (P <0.01).Conclusion 2.8ATA first treatment pressure re-lationship in severe ACOP promoting awake time,reduce the incidence of ACMP,improve the cure rate, should be widely applied.