包虫病的药物经济学评价研究

摘要

Objective To compare the economic effects of albendazole and mebendazole in the treatment of echinococcosis.Methods A total of 108 inpatients with echinococcosis from 2014 to 2015 were enrolled and they were randomly divided into albendazole group and mebendazole group,respectively.The cost ef-fectiveness analysis method of pharmacoeconomics was used for analysis and evaluation.Results The ef-fective rate in Albendazole treatment group was 57.9%,while which in mebendazole treatment group was 51%;the rate of cost-effectiveness(C/E)in albendazole group was 14.6%,while which in mebendazole group was 34.7%;the rate of adverse reactions in albendazole group was 3.5% and the rate of the adverse reaction in mebendazole group was 5.9%.Conclusion There was no significant difference between alben-dazole group and mebendazole group in the effective rate and the cure rate in the treatment of echinococco-sis.The economic cost of albendazole in treatment for echinococcosis was better.%目的 比较阿苯达唑和甲苯咪唑治疗包虫病的经济效果.方法 选择2014-2015年在新疆医科大学第一附属医院住院治疗的包虫病患者108例,随机分成阿苯达唑组和甲苯咪唑组,分别给予治疗.运用药物经济学的成本效果分析方法进行分析.结果 阿苯达唑组治疗的有效率为57.9%,甲苯咪唑组治疗的有效率为51.0%;阿苯达唑组的成本-效果比(C/E)为14.6%,甲苯咪唑组的 C/E为34.7%;阿苯达唑组的不良反应发生率为3.5%,甲苯咪唑组的不良反应发生率为5.9%.结论 阿苯达唑组和甲苯咪唑组方案治疗包虫病,临床总有效率无明显差异,阿苯达唑治疗包虫病的经济学成本较好.