急性百草枯中毒70例心肌损害分析

摘要

Objective To observe the myocardial injury in patients with parquet poisoning. Method Retrospective analysis was conducted on 70 cases of parquet poisoning to assess levels of myocardial enzymes, cardiac troponin I (cTnI), brain natriuretic peptide (BNP) and ECG changes.Result Levels of myocardial enzymes, cTnI, BNP increased gradually with the aggravation of poisoning degree, and these indexes of death group were significantly higher than those of survival group. ECG changes could be diverse and complex in patients with parquet poisoning.Conclusion Parquet poisoning may cause myocardial injury, and the injury will extend with the aggravation of poisoning degree.%目的：观察急性百草枯（paraquat ,PQ）中毒对心肌的损害，使该中毒患者得到更加全面的治疗。方法对PQ中毒患者70例血清心肌酶谱、肌钙蛋白I（cardiac troponin I,cTnI）、脑钠肽(brain natriuretic pcptide , BNP)的变化及心电图检查指标作回顾性分析。结果血清心肌酶谱及cTnI、BNP在PQ中毒急性期变化明显，且随中毒程度加深而增高，并有显著改变；上述指标在死亡组和存活组中的比较差异亦具有统计学意义（P均<0.05）。同时PQ中毒患者可出现多样性、复合性心电图改变。结论PQ中毒患者有较高的心肌损害发生率，中毒越重，心肌损害越明显，需要相应的治疗。