不同促性腺激素释放激素类似物对垂体反应性的作用

摘要

促性腺激素释放激素类似物分为激动剂与拮抗剂,在辅助生殖治疗中,主要用于抑制黄体生成素(LH)峰,预防卵泡早排,但两者对垂体反应性产生不同的作用.本文旨在讨论不同促性腺激素释放激素类似物对垂体反应性的影响,以及垂体外效应.%GnRH analogues,including GnRH agonists(GnRH-a) and antagonists(GnRH-ant),have been introduced in IVF program to prevent premature LH surge.The two kinds of GnRH analogues have different effects on pituitary response.This review summarizes the effects of GnRH-a or GnRH-ant on pituitary as well as extra-pituitary.