Objective To evaluate the clinical and pathological characteristics and CT manifestations of retroperitoneal malignant fibrous histiocytoma ( MFH ), so that to improve the ability of imaging diagnosis and differential diagnosis of this disease.Methods The clinical and CT findings of 15 patients with retroperitoneal MFH confirmed by operation and pathology were retrospectively analyzed comparatively with histological features.Results Among the 15 patients, 11 were men and 4 were women,the ages were over 36 years old in 13 cases.The major clinical symptoms of the retroperitoneal MFH were abdominal masses and bellyache.CT showed abdominal lobulated soft tissue masses, the average diameter of tumors was 12.5 cm,necrosis inside the tumors in 9 cases,hemorrhage in 7 and calcification in 6 were found.Heterogeneous enhancement in all cases and linear enhancement in 13 cases were demonstrated on contrast-enahnced CT.These tumors had marked cytological and nuclear pleomorphism, including 11 spoke-pleomorphism MFH, 3 giant cell MFH, 1 inflammatory MFH.Conclusion CT findings of retroperitoneal MFH are of certain characteristics,that can demonstrate the pathological features of this disease.%目的 探讨腹膜后恶性纤维组织细胞瘤(MFH)的临床、病理组织学特征及CT表现,提高对本病的诊断与鉴别诊断水平.方法 回顾性分析经手术病理证实的15例腹膜后MFH的临床及CT 表现,并与病理组织学改变相对照.结果 15例腹膜后MFH中,男11例,女4例,36岁以上13例,主要临床表现为腹部肿块和疼痛.15例CT平扫表现为腹膜后分叶状软组织肿块,肿瘤平均直径为12.5 cm,瘤内坏死9例,出血7例,钙化6例.增强扫描肿瘤不均匀强化,13例见分隔状强化.组织学上呈明显多形性,其中车辐状-多形性MFH 11例,巨细胞性MFH 3例,炎性MFH 1例.结论腹膜后MFH的CT 表现有一定特征性,能较好地反映病变的病理组织学特点.
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