超声弹性成像和造影在慢性乙型肝炎肝纤维化评估中的效果对比

摘要

Objective To evaluate the effect of ultrasound elastography and radiography in the assessment of hepatic fibrosis in chronic hepatitis B patients. Methods Seventy patients with chronic hepatitis B were en-rolled in our hospital from August 2014 to August 2016. Liver ultrasonography was performed in all patients. HAVTT1 and HAVTT2 were measured by visual method. SWV was measured by ultrasonic elasticity imaging. Re-sults With the increase of liver fibrosis,SWV test also increased,while HAVTT gradually shortened.The correct rates of HAVTT1 and HAVTT2 and SWV in the diagnosis of liver fibrosis were 72.36%,76.84% and 89.78%.The diagnostic accuracy of SWV was higher than that of HAVTT1 and HAVTT2,the difference was statistically sig-nificant(P<0.05).Conclusion Acoustic contrast measurement of HAVTT1 and HAVTT2 can reflect the chang-es of liver microcirculation,which is helpful to distinguish liver cirrhosis,fibrosis and no fibrosis. The measure-ment of SWV can reflect the difference of texture hardness of liver,which can be used as a kind of judgment on the degree and effect of hepatic fibrosis new method.%目的 探讨超声弹性成像和造影在慢性乙型肝炎肝纤维化评估中的效果.方法 选择2014年8月至2016年8月我院收治的慢性乙型肝炎73例为研究对象,对所有患者进行肝脏超声造影,采用目测法测量计算HAVTT1和HAVTT2,超声弹性成像测量SWV.结果 随着肝纤维化程度的增加,SWV测值也随之升高,而HAVTT则逐渐缩短.HAVTT1和HAVTT2及SWV诊断肝纤维化分期的正确率分别为:72.36%、76.84%及89.78%,SWV诊断正确率高于HAVTT1和HAVTT2,差异有统计学意义(P<0.05).结论 超声造影测量HAVTT1和HAVTT2可反映肝脏微循环变化,有利于区别肝硬化、纤维化及无纤维化,而测量SWV可反映肝脏的质地硬度差异,可作为判断肝纤维化程度和疗效的一种新方法.