ESWAN评估子宫肌瘤高强度聚焦超声消融术的应用研究

摘要

目的 分析子宫肌瘤高强度聚焦超声(HIFU)术后增强型T2*加权血管成像(ESWAN)信号的变化,探讨ESWAN的应用价值.方法 HIFU术前、后1 d对子宫肌瘤行常规MRI和ESWAN成像,测量ESWAN参数值并使用配对t检验进行比较.结果 子宫肌瘤HIFU术前和术后的幅度值分别为1624.59±53.07和1750.13±39.81,相位值为(0.12×10-2±0.81×10-2)Hz和(0.25×10-2±0.10)Hz,R2*值为(27.69±1.27)Hz和(24.19±1.20)Hz,T2*值为(34.66±2.07)ms和(36.46±2.14)ms.HIFU术后,幅度值、相位值和T2*值升高(P=0.04、P=0.91和P=0.45),R2*值降低(P=0.02).结论 ESWAN有助于评估子宫肌瘤HIFU术后的组织学变化.%Objective To explore the value of enhanced T2 star weighted angiography(ESWAN)in the treatment of uterine fibroids with high intensity focus ultrasound(HIFU) by analyzing the changes of ESWAN. Methods Uterine fibroids were detected through pelvic conventional MRI and ESWAN 1 day before and after HIFU operation. Different indexes of ESWAN were measured ,and differences were compared with the paired t-test. Results The preoperative and postoperative values of magnitude were 1624.59 ± 53.07 and 1750.13 ± 39.81, phase values were 0.0012 ± 0.0081 Hz and 0.0025 ± 0.1063 Hz,R2*value were 27.69 ± 1.27 Hz and 24.19 ± 1.20 Hz,and T2*values were 34.66 ± 2.07 ms and 36.46 ± 2.14 ms. After HIFU operation,magnitude value,phase value and T2*value were higher(P=0.04,P=0.91 and P=0.45),and R2*value was lower(P=0.019). Conclusions ESWAN can provide more information about histopathologic changes of uterine fibroids after HIFU.