Objective To study the correlation between the double scanning arterial enhancement characteris-tics and tumor differentiation degree in hepatocellular carcinoma (HCC) with a use of four phases dynamic enhanced CT. Methods Sixty cases of HCC patients confirmed by surgery were performed MSCT four phases dynamic en-hanced CT to collected a total of 62 tumor lesions. Firstly, those 62 tumor lesions in accordance with the enhancement characteristics of tumor blood vessels in dual arterial phase were compared with liver parenchyma density at the same period. Then they were grouped as following: tumor parenchyma strengthening group (group A), tumor blood vessels strengthening group (including the tumor lesion involving both tumor parenchyma and vessels enhancing) (group B), and cancer with no strengthening group (group C). Moreover, tumor lesions were also divided into three groups accord-ing to differentiation degree: high differentiation group (high differentiation and high-middle differentiation), middle differentiation group (middle differentiation), low differentiated group (medium-low differentiation and low differentia-tion). Finally, a compared analysis was made between the improved characteristic of double arterial lesions and tumor pathological differentiation. Results The diagnose power of tumor blood vessels had been greatly increased in artery early stage, and it would be increasing as the differentiation degree down. In addition, a significant association be-tween double arterial lesions improved characteristics and differentiation degree of tumor pathology was identified ( P<0.05). Conclusion A significant association between the double scanning arterial enhancement characteristics of four phases dynamic enhanced CT and tumor differentiation degree was found in HCC. The characters of MSCT four phas-es dynamic enhanced CT in double arterial phase can provide more reliable prognostic information in clinical.%目的：应用多层螺旋CT（MSCT）对肝细胞肝癌进行四期增强扫描，探讨双动脉期强化特点与肿瘤病理分化程度之间的关系。方法收集60例行MSCT四期动态增强扫描并经手术病理证实的肝细胞肝癌患者的62个肿瘤病灶。62个肿瘤病灶根据双动脉期肿瘤内血管强化的特点、内肿瘤实质与同期肝实质密度的对比结果分为肿瘤实质强化组（A组）、肿瘤血管强化组（包括肿瘤实质强化与肿瘤血管强化同时存在的肿瘤病灶）（B组）、肿瘤无明显强化组（C组）；根据分化程度分为高分化组（高分化和高-中分化）、中分化组（中分化）、低分化组（中-低分化和低分化）。将病灶双动脉期3组强化特点与3组肿瘤病理分化程度进行对比研究。结果MSCT四期增强扫描动脉早期大大提高了肿瘤血管的显示率，随着分化程度的降低，动脉期早期肿瘤血管显示增多。病灶双动脉期强化特点与肿瘤病理分化程度存在显著相关性（P＜0．05）。结论肝细胞肝癌CT四期动态增强扫描双动脉期强化特点与肿瘤病理分化程度之间存在相关性，MSCT四期增强扫描双动脉期表现特点能够为临床提供更多的预后信息。
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