Objective To compare the diagnosis of total tumor perfusion and maximum diameter measurement in assessing CT scan imaging in patients with hepatocellular carcinoma (HCC). Methods Fifty-six patients with hepatocellular carcinoma between January 2013 and January 2016 were recruited in this study. The 320 row volume CT perfusion imaging was performed. The parameters of hepatic perfusion were calculated, including hepatic artery perfusion (HAP),portal vein perfusion (PVP) and hepatic perfusion index (HAPI). The total tumor perfusion and the maximum diameter of tumors were applied to record the parameters of tumoral, peritumoral and normal liver tissues. Results The HAP and HAPI of tumors were much higher,while the PVP of tumors were much lower than those in peritumoral or normal liver tissue by both measurements (P<0.05);there was no significant difference between parameters of tumors by both measurements (P>0.05),and there was also no significant difference between parameters by two doctors who measure the parameters (P>0.05). Conclusion The total tumor perfusion or maximum diameter measurement in assessing CT scan imaging in patients with hepatocellular carcinoma is good,but the latter might be convenient and simple.%目的 比较全肿瘤灌注测量与轴位最大层面测量320排容积CT灌注成像诊断肝细胞癌的优缺点.方法 56例肝细胞癌患者接受320排容积CT灌注成像检查,采用全肿瘤灌注和肿瘤轴位最大层面灌注测量肿瘤、瘤旁肝组织和正常肝组织的肝动脉灌注量(HAP)、门静脉灌注量(PVP)和肝动脉灌注指数(HAPI).结果 瘤体各灌注参数与瘤周肝组织或正常肝组织比,差异均有显著统计学意义(P<0.05);全肿瘤灌注测量值与轴位最大层面测量法得到的各参数均无统计学差异(P>0.05);两名医生应用两种方法测量获得的三种组织测量值无显著性统计学差异(P>0.05).结论 使用320排容积CT灌注成像检查肝细胞癌瘤体,应用轴位最大层面法测量可以获得同样的测量值,但减轻了工作量.
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