青少年心血管代谢性健康风险与身体活动的剂量效应

摘要

In order to clarify dose-effect relations between medium and high intensity physical activities and obe-sity, hypertension, dyslipidemia and metabolic syndrome of teenagers, so as to determine medium and high intensity physical activity doses recommended for preventing cardiometabolic health risks of teenagers, the authors selected 3162 aged 12~17 teenagers in US Health and Nutrition Survey in 200-2004 and 2005-2006 as their research sub-jects, measured the height, weight, waist circumference, blood pressure, blood sugar, blood fat, food intake and physical activity levels of the testees, used the fractional polynomial model to respectively analyze the relations be-tween medium and high intensity physical activity times and cardiometabolic health risks (obesity risk, hypertension risk, dyslipidemia risk and metabolic syndrome risk), worked out their dose-effect curves by fitting, and revealed the following findings:there were dose-effect relations between medium and high intensity physical activity times and obesity risk, hypertension risk, low and high density lipoprotein risks, high triglyceride risk and metabolic syndrome risk of teenagers;these cardiometabolic health risks tended to decrease in a curvilinear manner as daily medium and high intensity physical activity times increased.%为阐明中高强度身体活动与青少年肥胖、高血压、血脂异常和代谢综合征之间的剂量效应，以确定预防青少年心血管代谢性健康风险的中高强度身体活动推荐量。选取2003-2004、2005-2006年美国健康营养调查中3162名6~17岁的青少年作为研究对象，测量受试者的身高、体重、腰围、血压、血糖、血脂、膳食摄入情况以及身体活动水平，采用分数多项式模型分别分析中高强度身体活动时间与心血管代谢性健康风险(肥胖风险、高血压风险、血脂异常风险和代谢综合征风险)之间的关系，并拟合出它们之间的剂量效应曲线。结果显示：中高强度身体活动时间与青少年肥胖风险、高血压风险、低高密度脂蛋白风险、高甘油三酯风险和代谢综合征风险之间存在着剂量效应，这些心血管代谢性健康风险随着每天中高强度身体活动时间的增加而呈曲线下降的趋势。