泊沙康唑干混悬剂的制备及稳定性研究

摘要

目的：制备一种稳定的泊沙康唑干混悬剂，该干混悬剂包括泊沙康唑3.0%～4.0%、填充剂90%～95%、作为润湿剂的表面活性剂0.8%～1.0%。按照本发明制备的干混悬剂，以固体形式储存，方便携带，运输方便，稳定性好。服用前加水适量配制成混悬液，充分摇匀，口服。%The presentinvention relates to a stable dry suspension posaconazple and its preparation method the dry suspension including posaconazole 3.0%to 4.0% from 90% to 95% filler as awetting agent surfactants 0.8% to1.0%.Prepared in accordance with the present invention dry suspension stored in solid form easy to carry easy to transport good stability before taking the amount of water formulated into s suspension shake it well orally.