当飞利肝宁胶囊防治抗结核药物性肝损伤临床分析

摘要

目的：探讨当飞利肝宁胶囊防治抗结核药物性肝损伤的保肝作用。方法：将121例初治结核病患者随机分为两组，实验组61例，对照组60例。实验组加用当飞利肝宁胶囊，对照组未加用任何保肝药。每月复查肝功能，若出现轻度肝功损伤则加用当飞利肝宁胶囊保肝治疗。结果：肝损伤发生率对照组显著高于实验组（P<0.05），差异有统计学意义；轻度肝损害者肝功能治愈率达80%，有效率100%。结论：当飞利肝宁胶囊能有效预防和治疗抗结核药物所致肝损伤。%Objective:To discuss the hepatoprotective effect of Dangfei Liganning capsule in liver injury induced by anti-tuberculosis drugs.Methods:121 patients of initial treatment tuberculosis were randomly devided into two groups,the treatment group (n=61) and the control group (n= 60).meanwhile the treatment group was given Dangfei Liganning capsule,but the control group without any hepatoprotective drug.Monitored liver function every month,and given Dangfei Liganning capsule when slight drug-induced liver injury. Results:The incidence of liver injury were significantly higher than those in the experimental group, the difference was statistically significant (P<0.05);Liver damage control group of patients with mild liver damage liver function cure rate of 80%, the effective rate was 100%.Conclusion:Dangfei Liganning capsule effectively prevent and cure liver injury induced by anti-tuberculosis drugs.