肝纤维化非创伤性诊断方法的研究现状与评价

摘要

肝纤维化是一个慢性的、渐进性的过程,其持续发展的最终结果为肝小叶结构改建、假小叶形成,最终发生肝硬化.近年来已认识到,肝纤维化在去除病因和经过治疗后可以逆转,所以早期诊断对肝纤维化的逆转至关重要.该文综述了肝纤维化的诊断方法,重点介绍肝纤维化的非创伤性诊断方法的临床应用价值及其局限性.%Liver fibrosis is a chronic and progressive disease that can eventually evolve into cirrhosis.As realized in recent years, after etiology analysis, liver fibrosis could be reversed by receiving appropriate treatment.Thus, the early diagnosis is essensial for reversing hepatic fibrosis.This review summarizes the diagnosis means of hepatic fibrosis, and mainly focuses on the clinical application value and limitations of nontraumatic methods to diagnose hepatic fibrosis.