西甲硅油在克罗恩病结肠镜检查和治疗中的应用分析

摘要

目的：分析西甲硅油在克罗恩病结肠镜检查和治疗中的应用效果。方法连续选择96例克罗恩病便秘患者，随机分为对照组[单用复方聚乙二醇电解质散（PEG-ELS）]48例和观察组（PEG-ELS 联合西甲硅油）48例，所有患者均加用莫沙必利，对比观察效果。结果观察组的肠道清洁比例高于对照组，结肠内气泡存在程度低于对照组，差异有统计学意义（P ＜0．05），视野清晰 A、B 级显著增多。观察组患者腹胀程度显著轻于对照组，差异有统计学意义（P ＜0．05），无腹胀比例增多，中、重度腹胀比例减少。观察组显示的病变数目和长度较多，选择治疗的患者中观察组成功率高于对照组，差异有统计学意义（P ＜0．05）。结论西甲硅油可明显提高克罗恩病便秘患者结肠镜检查和治疗的应用效果。%[Obstract] Objective To analyze the application effect of simethicone in colonscopy and treatment of Crohn's disease.Methods A total of 96 constipation patients with Crohn's disease were continuously selected, who were divided randomly into control group (single polyethylene glycol-electrolyte lavage solution,PEG-ELS)including 48 cases and observation group (PEG-ELS combined with simethicone)including 48 cases. All patients were treated with Mosapride.The effects of two intestinal cleaning methods were compare.Results Intestinal cleaning ratio in observation group was significantly higher than that in the control group (P <0.05),presence degrees of bubbles in the colon were significantly lower than that in the control group and class A and B ken significantly increased in observation group.Degrees of abdominal distension in observation group were significantly less than that of the control group (P <0.05),the proportion of no abdominal disten-sion cases increased and the proportion of moderate and severe distension cases decreased in observation group. The observation group showed significant increase in the number and length of the lesion,and the success rate of treated persons in observation group was higher than that of the control group (P <0.05).Conclusion Simethicone can significantly improve efficacy of colonoscopy examination and treatment for Crohn's and consti-pation patients.