解毒破瘀法抑制三阴性乳腺癌复发与转移的临床研究

摘要

ABSTRACT:OBJECTIVE To observe the clinical efficacy of method of detoxification and blood stasis dissipating on the inhi-bition of recurrence and metastasis of triple negative breast cancer(TNBC).METHODS 40 cases of TNBC patients after op-eration were randomly divided into the control group and the treatment group,with 20 cases in each group.The control group was treated according to syndrome differentiation.The treatment group was treated with the method of detoxification and blood stasis dissipating beside the syndrome differentiation.Observe the disease free survival (DFS) of patients after 3-year treat-ment.RESULTS The DFS in the treatment group after 3-year treatment was 100%,while the control group 75% (P <0.05).CONCLUSION The method of detoxification and blood stasis dissipating can effectively inhibit the recurrence and me-tastasis of triple negative breast cancer.%目的：观察解毒破瘀法抑制三阴性乳腺癌（TNBC）复发与转移的临床疗效。方法40例三阴性乳腺癌术后患者随机分为治疗组和对照组，各20例，对照组根据辨证施治随证加减，治疗者在辨证施治的同时加用解毒破瘀法，治疗3年，观察3年无病生存率（DFS）。结果治疗组20例患者3年 DFS 为100％，对照组为75％，P ＜0．05。结论解毒破瘀法能有效抑制三阴性乳腺癌复发及转移。