移植嗅鞘细胞修复神经损伤作用的研究进展

摘要

近年来细胞移植治疗疼痛的研究已成为医学研究的热点，其中嗅鞘细胞（olfactory ensheathing cell，OECs）最受关注，它具有中枢和外周神经胶质细胞的特性，既像雪旺氏细胞促进轴突的生长，又像星形胶质细胞那样能在中枢神经系统中存活，正是这种复合体性使其成为治疗神经损伤最佳候选细胞之一，本文对移植 OECs 修复神经损伤作用的研究进展进行综述。%The treatment of pain with cell transplantation has become a focus of medical re-search.Among different candidate cells,olfactory ensheathing cells(OECs)raise considerable con-cerns due to their characteristics of glial cells of the central and peripheral nervous systems.OECs can not only promote axonal growth like Schwann cells,but also survive in the central nervous system like astrocytes.The property of complex makes them optimal candidate cells for the treat-ment of nerve injury.This review presents the research progress in transplantation of OECs for nerve injury repair.