Objective : To summarize the clinicopathologic features of the cases of cotyldonoid dissecting leiomyoma of the uterus. Methods : To retrieve public published articles to find proper cases with searching words in both English and Chinese , such as cotyledonoid dissecting leiomyoma of the uterus , cotyledonoid leiomyoma of the uterus . sternherg tumor, grape - like leiomyoma. And search such cases diagnosed and treated in our hospital from 2000 to 2010.Meta - analysis was carried out for these cases. Results : The age of onset was in the range of 23 to 73 years , the median age was 43 years. Lacking typical clinical manifestations, most patients saw a doctor because of pelvic mass , menstruation change and irregular vaginal bleeding. Macroscopically , the extrauterine tumor looked like placenta tissue , the intrauterine part irregularly extended into the myometrium. Microscopically, the tumors lacked nuclei atypical. Operation was the main treatment. None recurrence was found in follow - up ranged from 1 moth t0 41 years. Conclusion :Although the appearance of cotyldonoid dissecting leiomyoma of the uterus looks like malignant tumor,it is benign as a special uterus myoma. Overtreatment could be avoided according to pathologic especially frozen pathologic result.%目的:总结迄今国内外公开发表的以及我院2000年至2010年诊治的子宫绒毛叶状分割性平滑肌瘤(cotyledonoid dissecting leiomyoma of the uterus)的临床及病理特点.方法:以子宫绒毛叶状分割性平滑肌瘤、子宫绒毛叶状平滑肌瘤、cotyledonoid dissecting leiomyoma of the uterus、cotyledonoid leiomyoma of the uterus、sternberg tumor、grape-like leiomyoma为检索词检索国内外公开发表的文献,并结合我院诊治的3例病例进行荟萃分析.结果:发病年龄为23-73岁,平均年龄43.55岁.缺乏典型的临床症状.大体标本宫壁外部分呈胎盘小叶样,宫壁内部分呈分割性改变,镜下细胞无异型.治疗以手术为主,术后随访1个月至41年不等,无复发病例.结论:子宫绒毛叶状分割性平滑肌瘤虽外观酷似恶性肿瘤,实为特殊类型的良性子宫平滑肌瘤,结合病理特别是术中冰冻病理检查可避免过度治疗.
展开▼
