18氟-脱氧葡萄糖和11碳-乙酸PET显像在原发性肝细胞癌中的应用价值

摘要

Hepatocellular carcinoma (HCC) is one of the most common causes of death in China. According to the recent research, the diagnostic accuracy of 18F-fluorodexoxyglucose (18F-FDG) positron emission tomography (PET) remains questionable for primary HCC but seems to be more promising for predicting prognosis and monitoring therapeutic effect. At the same time, combine both18 F-FDG and 11C-acetate (11C-ACT) PET would have an in1 cremental value and complementary advantage when compared with single-tracer imaging in the detecting HCC and metastasis.%原发性肝细胞肝癌( hepatocellular carcinoma,HCC)是中国最常见的致死性疾病.18氟-脱氧葡萄糖(18F-fluorodexoxyglucose,18F-FDG) PET显像对HCC的诊断准确率欠佳,但它对HCC的预后评估及疗效监测有很大作用.同时,对于HCC原发灶和转移灶的检测,18F-FDG和11碳-乙酸(11C-acetate,11C-ACT)两种示踪剂联用比单示踪剂PET显像更具有优势.