循环 miRNA 在非小细胞肺癌诊断治疗及预后判断中的价值

摘要

MicroRNAs (microRNAs,miRNAs)are a species of small non -coding single stranded RNA in regula-ting gene transcription level after participation,widely involved in the regulation of tumor occurrence and develop-ment.Circulating miRNAs are found in the peripheral blood,many recent studies have shown that circulating miRNAs as new clinical biomarkers are important for the diagnosis,therapeutic effect and prognosis of lung cancer.%微小 RNA（microRNAs，miRNAs）是一类参与基因转录后水平调控的小分子非编码 RNA，广泛参与肿瘤发生发展等过程的调节。循环 miRNAs 是在外周血中发现的 miRNAs，新近研究资料显示，循环 miR-NAs 作为一种新型生物标志物可能在肺癌的诊断、疗效评估和预后判断中有着重要的作用和价值。