Objective To investigate the effect of emergency craniotomy clipping combined with ventricular puncture in treating middle and high grade intracranial rupture. Methods A total of 62 cases of arterial aneurysm complicating subarachnoid hemorrhage were selected. Among them ,32 cases of craniotomy clipping combined with ventricular puncture were taken as the observation group,while 30 cases of only craniotomy were as the control group. The treatment effect of the two groups was ob-served. Results (1)The patients with better postoperative recovery in the observation group were significantly more than those in the control group,while the patients with poor recovery or death were significantly less than those in the control group ,the differ-ences were statistically significant(P<0.05);the postoperative complications had no statistical difference between the two groups (P>0.05);(2)the patients with hydrocephalus symptoms and the proportion for performing ventricle/lumbar-celiac bypass operation in the observation group were significantly lower than those in the control group ,the difference was statistically significant (P<0.05). Conclusion Craniotomy clipping combined with ventricular puncture can significantly reduce the intracranial pressure and decreases the injury of cerebral important functional regions and increase the postoperative survival quality of the patients in treating middle and high grade intracranial rupture.%目的探讨急诊开颅夹闭联合脑室穿刺治疗中高级别颅内破裂的效果。方法选取62例动脉瘤伴蛛网膜下腔出血患者，其中应用开颅夹闭联合脑室穿刺治疗的32例患者作为观察组，仅应用开颅夹闭治疗的30例患者作为对照组，观察两组治疗效果。结果（1）观察组术后恢复良好患者明显多于对照组，而恢复差及死亡患者明显少于对照组，差异有统计学意义（P<0.05）；两组术后并发症比较，差异无统计学意义（P>0.05）；（2）观察组患者随访中出现脑积水症状及行脑室/腰椎-腹腔分流术比例明显低于对照组，差异有统计学意义（P<0.05）。结论开颅夹闭联合脑室穿刺治疗中高级别颅内破裂效果可明显降低颅压，减少脑重要功能区的损伤，提高术后患者生存质量。
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