肝胆外科手术部位感染(SSI)的病原菌和药敏分析

摘要

Objective To discuss the distribution,drug resistance and preventing measures of the pathogenic microbiology of surgical site infection(SSI) in hepatobiliary and gall surgery in Hubei Huanggang. Methods Collected the specimen which came from the inpatient in the departments of liver and gall surgical SSI of Hubei Huanggang from 2008 to 2010,and isolated and identified the bacteria using the Beckman Coult System, used the Kirby-Bauer to do the drug sensitive test with CLSI2009 as a standard. Results There were 1 416 bacterial strains (gram-positive bacteria accounts for 37% while gram-negative accounts 63%) in 10 264 specimen,the positive rate was 13. 8%. The common bacteria were enterobacters,Staphy-lococcus pyogenes aureus, Enterococcus and coagulase negative staphylococci. Conclution Enterobacter, Staphylococcus pyogenes aureus, Knterococcus and coagulase negative staphylococci are the major bacteria of SSI in the departments of liver and gall surgical in Hubei Huanggang,the prevalences are differences in different surgical position,and the percent of infection can reduce by effective preventive measures.%目的 探讨肝胆外科手术部位感染(surgical site infection,SSI)影响因素、病原菌分布情况和感染预防措施.方法 对2008年1月～2010年12月期间,湖北省黄冈地区肝胆外科手术部位(SSI)住院送检的10 264例标本进行培养,并采用BECKMAN COULT全自动细菌分析系统鉴定分离菌,K-B纸片扩散法进行药敏试验,以CLSI2009年版标准判读结果.结果从10 264份送检标本中检出病原菌1 416株,阳性率为13.8%;其中革兰氏阳性菌524株,占37%,革兰氏阴性菌892,占63%.结论 大肠埃希菌、金黄色葡萄球菌等是造成肝胆外科手术部位感染的主要病原菌.合理使用抗生素对于有效预防和控制手术部位感染(surgical site infection,SSI)至关重要.